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1.
Open Bioinformatics Journal ; 15, 2022.
Article in English | Scopus | ID: covidwho-2054703

ABSTRACT

Aims: This study investigates an unsupervised deep learning-based feature fusion approach for the detection and analysis of COVID-19 using chest X-ray (CXR) and Computed tomography (CT) images. Background: The outbreak of COVID-19 has affected millions of people all around the world and the disease is diagnosed by the reverse transcription-polymerase chain reaction (RT-PCR) test which suffers from a lower viral load, and sampling error, etc. Computed tomography (CT) and chest X-ray (CXR) scans can be examined as most infected people suffer from lungs infection. Both CT and CXR imaging techniques are useful for the COVID-19 diagnosis at an early stage and it is an alternative to the RT-PCR test. Objective: The manual diagnosis of CT scans and CXR images are labour-intensive and consumes a lot of time. To handle this situation, many AI-based solutions are researched including deep learning-based detection models, which can be used to help the radiologist to make a better diagnosis. However, the availability of annotated data for COVID-19 detection is limited due to the need for domain expertise and expensive annotation cost. Also, most existing state-of-the-art deep learning-based detection models follow a supervised learning approach. Therefore, in this work, we have explored various unsupervised learning models for COVID-19 detection which does not need a labelled dataset. Methods: In this work, we propose an unsupervised deep learning-based COVID-19 detection approach that incorporates the feature fusion method for performance enhancement. Four different sets of experiments are run on both CT and CXR scan datasets where convolutional autoencoders, pre-trained CNNs, hybrid, and PCA-based models are used for feature extraction and K-means and GMM techniques are used for clustering. Results: The maximum accuracy of 84% is achieved by the model Autoencoder3-ResNet50 (GMM) on the CT dataset and for the CXR dataset, both Autoencoder1-VGG16 (KMeans and GMM) models achieved 70% accuracy. Conclusion: Our proposed deep unsupervised learning, feature fusion-based COVID-19 detection approach achieved promising results on both datasets. It also outperforms four well-known existing unsupervised approaches. © 2022 Ravi and Pham.

2.
IEEE Transactions on Engineering Management ; 2021.
Article in English | Scopus | ID: covidwho-1367269

ABSTRACT

Quick, early, and precise detection is important for diagnosis to control the spread of COVID-19 infection. Artificial Intelligence (AI) technology could certainly be used as a modulating tool to ease the detection, and help with the preventive steps further. Convolutional neural networks (CNNs) have achieved state-of-the-art performance in many visual recognition tasks. Nevertheless, most of these state-of-the-art networks highly rely on the availability of a high amount of labeled data, being an essential step in supervised machine learning tasks. Conventionally, this manual, mundane, and time-consuming process of annotating images is done by humans. Learning to localize or detect COVID-19 infection masks in our specific case study typically requires the collection of CT scan data that has been labeled with bounding boxes or similar annotations, which generally is limited. A technique that could perform such learning with much less annotations, and transfer the learned proposals that are algorithm-driven to generate more synthetic annotated samples would be helpful And quite valuable. We present such a technique inspired by weakly trained mask region based convolutional neural networks (R-CNN) architecture for localization, in which the number of images with their pixel-level masks can be a small proportion of the total dataset, and then further improvise CNNs by inversely generating dense annotations on-the-go using an algorithmic-based computational approach. We focus on alleviating the bottleneck associated with deep learning models needing annotated data for training in an intuitive reverse engineering fashion through this work. Our proposed solution can certainly provide the prospect of automated labeling on-the-fly, thereby reducing much of the manual work. As a result, one can quickly train a precise COVID-19 infection detector with the leverage of autonomous frame-by-frame machine generated annotations. The model achieved mean precision accuracy (%) of 0.99, 0.931, and 0.8 for train, validation, and test set, respectively. The results demonstrate that the proposed method can be adopted in a clinical setting for assisting radiologists, and also our fully autonomous approach can be generalized to any detection/recognition tasks at ease. IEEE

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